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Fire Technology - Tunnels are nowadays key elements in transport networks worldwide. To achieve a safe and efficient operation, a proper integration and design of Mechanical, Electrical and...  相似文献   
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Type 2 diabetes mellitus patients are at significant risk of cardiovascular disease, however, the pathophysiology of these complications is complex and incompletely known in this population. The aim of this study was to compare the serum proteome of patients with type 2 diabetes mellitus presenting or not presenting cardiovascular disease with non-diabetic subjects to find essential proteins related to these cardiovascular complications. This cross-sectional study compares the serum proteome by a combination of protein depletion with 2D-DIGE (2-dimension Difference Gel Electrophoresis) methodology. The proteins differentially expressed were identified by MALDI TOF/TOF (Matrix-assisted laser desorption/ionization and Time-Of-Flight ion detector) or LC-MS/MS (Liquid Chromatography coupled to Mass-Mass Spectrometry). Type 2 diabetes mellitus patients with cardiovascular disease showed higher expression of plasma retinol binding protein and glutathione peroxidase-3 compared to those without cardiovascular disease and non-diabetic controls. These results show that proteins related to the inflammatory and redox state appear to play an important role in the pathogenesis of the cardiovascular disease in the type 2 diabetes mellitus patients.  相似文献   
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A fast and reliable method for anthocyanin extraction and identification by HPLC‐DAD‐ESI/MS‐QTOF was used to analyse the anthocyanin composition of commercial red fruit juices (blackberry, redcurrant and pomegranate), purees (strawberry, cherry and raspberry) and concentrates (elderberry, blueberry and red grape). The anthocyanin profile of black carrot juice is also reported. The extraction and analysis method allowed us to detect and quantify a wide range of individual anthocyanins in a simple and rapid way. Pelargonidin‐3‐glucoside was detected in redcurrant for the first time and petunidin‐3‐galactoside quantified for the first time in blueberries. Considering the health benefits that have been associated with anthocyanin consumption, all these fruit and vegetables processed products could appear as a good source of this group of phytochemical compounds for their direct consumption or their use as ingredients for the design of new food product or food supplements.  相似文献   
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GIF animations are silent image sequences widely used on the web thanks to their wide support and portability. In this work, we propose an original technique based on data hiding, to add sound tracks in GIF animations. Data hiding is usually used to embed security codes in a host medium to prevent from illegal copying or to protect copyrights (watermarking) or to send secret messages to a dedicated receiver (steganography). We propose to use host GIF images as a “transmission channel” to convey “hidden” sound bits with lowest perceptual image distortion and without altering the wide portability of the GIF format, by means of data hiding. The inserted bits are neither secret nor intended for security issues. They are intended to be played by an audio player synchronously with the GIF player to add sound to the GIF animation. The embedding process is a low complexity, luminance based steganography algorithm, that slightly modifies the pixels colors of the GIF images to insert the sound bits. The extraction of the inserted audio is completely blind: the audio is directly extracted from the pixels of each cover image. The proposed GIF voicing was tested with different GIF sequences (cartoons and real scenes) and no audio degradation was reported while a slight, most imperceptible, color modification was noticed in case of an important amount of inserted data. The cover images have undergone objective quality criteria and informal subjective evaluation and has proved to be of good quality.  相似文献   
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BACKGROUND: Fusarium graminearum and F. verticillioides are two very important mycotoxigenic species as they cause diverse diseases in crops. The effects of constant and cycling temperatures on growth and mycotoxin production of these species were studied on soybean based medium and on irradiated soya beans. RESULTS: F. graminearum grew better when was incubated at 15, 20 and 15–20 °C (isothermal or cycling temperature) during 21 days of incubation. Maximum levels of zearalenone and deoxynivalenol (39.25 and 1040.4 µg g?1, respectively) were detected on soya beans after 15 days of incubation and the optimal temperature for mycotoxin production was 15 °C for zearalenone and 20 °C for deoxynivalenol. F. verticillioides grew better at 25 °C in culture medium and at 15/20 °C and 15/25 °C on soybean seeds. Fumonisin B1 was produced only in culture medium, and the maximum level (7.38 µg g?1) was found at 15 °C after 7 days of incubation. CONCLUSION: When growth and mycotoxin production under cycling temperatures were predicted from the results under constant conditions, observed values were different from calculated for both species and substrate medium. Therefore, care should be taken if data at constant temperature conditions are to be extrapolated to real field conditions. Copyright © 2012 Society of Chemical Industry  相似文献   
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Fusion welding of steel to aluminum is difficult due to formation of different types of Fe-Al intermetallics (IMs). In this work, 2 mm-thick steel was joined to 6 mm aluminum in overlap configuration using a 8 kW CW fiber laser. A defocused laser beam was used to control the energy input and allow melting of the aluminum alone and form the bond by wetting of the steel substrate. Experimentally, the process energy was varied by changing the power density (PD) and interaction time separately to understand the influence of each of these parameters on the IM formation. It was observed that the IM formation is a complex function of PD and interaction time. It was also found that the mechanical strength of such joint could not be simply correlated to the IM layer thickness but also depends on the area of wetting of the steel substrate by molten aluminum. In order to form a viable joint, PD needs to be over a threshold value where although IM growth will increase, the strength will be better due to increased wetting. Any increase in interaction time, with PD over the threshold, will have negative effect on the bond strength.  相似文献   
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